ABSTRACT
No disponible
Subject(s)
Humans , Pulmonary Disease, Chronic Obstructive/physiopathology , Dyspnea/physiopathology , Depression/epidemiology , Anxiety/epidemiology , Severity of Illness Index , Airway Obstruction/diagnosis , Psychometrics/instrumentation , Diagnosis, Differential , Oxygen Inhalation Therapy , Breathing Exercises , Pulmonary Disease, Chronic Obstructive/drug therapy , Bronchodilator Agents/therapeutic useSubject(s)
Hemothorax/diagnosis , Adult , Drainage , Hemothorax/therapy , Humans , Male , ThoracoscopyABSTRACT
OBJECTIVE: To evaluate the use in non-sputum samples of a commercial molecular amplification kit (LCx MTB, Abbott Diagnostica) (LCx) for the diagnosis of tuberculosis. MATERIAL AND METHOD: Ninety-nine non-sputum samples from the same number of patients (bronchoalveolar, pleural and ascitic fluid, fecal samples, blood cultures, biopsies from different sites, cerebrospinal fluid, urine and gastric juices) and 14 sputum samples (10 from patients clinically suspected of having tuberculosis and 4 from patients diagnosed of tuberculosis and undergoing appropriate treatment for at least one month). All samples were LCx processed according to the manufacturer's instructions. The reference diagnosis was obtained by the Löwestein-jensen method and when results were inconsistent, we took into account the degree of clinical suspicion, response to treatment and histology. RESULTS: Seven of the 99 samples were positive by the LCx technique, and 6 of the 7 were also LJ positive; 1 could not be evaluated because of culture contamination. One LJ positive culture was LCx negative. Only one sample was positive by Ziehl-Neelsen (ZN) staining. Ninety-two samples were LCx negative, with 91 showing no growth at all. Sensitivity was 86% and specificity 98%. Atypical mycobacteria were detected in 4 cases, all of which were LCx negative. CONCLUSIONS: Diagnosis of tuberculosis by applying the LCx system to various types of samples other than sputum is simple, rapid, sensitive and specific.
Subject(s)
Mycobacterium tuberculosis/isolation & purification , Sputum/microbiology , Tuberculosis, Pulmonary/diagnosis , Humans , Nucleic Acid Amplification Techniques , Tuberculosis, Pulmonary/microbiologySubject(s)
Lung Diseases/etiology , Nocardia Infections/etiology , beta-Thalassemia/complications , Adult , Female , Humans , India/epidemiology , Lung Diseases/diagnosis , Lung Diseases/epidemiology , Nocardia Infections/diagnosis , Nocardia Infections/epidemiology , Radiography, Thoracic , Spain/epidemiology , United States/epidemiologyABSTRACT
We report our experience in 8 patients with osteochondroplastic tracheopathy and consider the importance of its diagnosis y biopsy in order to confirm histology and if possible etiology, because specific treatment could change the course of the disease. Methods such as radiology, CT-scan, respiratory function tests only give diagnostic suspicion, which is a previous step before confirmation by bronchoscopy with biopsy. To date, with the exception of a few cases, the diagnosis is made by necropsy. Thus, this justifies our emphasis in the diagnosis of this rare disease when it is suspected in living patients.
